microarray dataset gse138614 (Biotechnology Information)
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Microarray Dataset Gse138614, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/microarray+dataset/dataset+gse138614+microarray/pmc13123086-29-1-18
Average 86 stars, based on 1 article reviews
Images
1) Product Images from "TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination"
Article Title: TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination
Journal: Journal of Neuroinflammation
doi: 10.1186/s12974-026-03769-4
Figure Legend Snippet: TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( GSE138614 ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm
Techniques Used: Expressing, Control, Gene Expression, Microarray, Quantitative RT-PCR, Western Blot, Immunofluorescence, Marker
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